Butylone, also known as β-keto-N-methylbenzodioxolylbutanamine, is an entactogen, psychedelic, and stimulant psychoactive drug of the phenethylamine chemical class. Butylone was first synthesized by Koeppe, Ludwig, and Zeile in 1967. It remained an obscure product of academia until 2005
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Butylone can be synthesized in a laboratory via the following route: 3,4-methylenedioxybutyrophenone dissolved in dichloromethane to bromine gives 3′,4′-methylenedioxy-2-bromobutyrophenone.
这个产品,然后溶解的二氯甲烷和加入到水溶液中的甲胺(为40%)。 HCl随后加入。 该含水层被去除和碱性,通过使用碳酸氢钠。 提取胺醚的使用。 获得butylone一滴醚和HCl溶液
Butylone acts in a similar way as MDMA and Methylone, it causes an increase in extracellular monoamine levels
Butylone was first synthesized by Koeppe, Ludwig and Zeile which is mentioned in their 1967 paper. It remained an obscure product of academia until 2005 when it was sold as a designer drug.[1] Butylone shares the same relationship to MBDB as methylone does to MDMA (“Ecstasy”). Formal research on this chemical was first conducted in 2009, when it was shown to be metabolised in a similar manner to related drugs like methylone
Butylone,也称为β-酮-N-methylbenzodioxolylbutanamine(βk-MBDB),是一个entactogen,迷幻,并刺激精神药物的苯乙胺的化学类。 这是β-酮(取代卡西酮)的模拟MBDB和取代methylenedioxyphenethylamine模拟buphedrone
有三种主要代谢途径bk-MBDB如图所示。 作为结果的demethylenation随后通过邻-甲基化bk-MBDB metabolises成4-哦-3-MeO和3-哦-4-MeO代谢物的人尿液。 第二个途径是β-酮的减少进入的β-酮的减少代谢物。
第三途径是一个N-脱成N-dealkyl代谢物。 第二个途径的发生更多的途径有三个。 最常见的代谢产物是4-哦-3-MeO代谢物。 代谢物含有一种羟基组将排泄作为他们的物尿
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