Butilona em pó

Butylone, também conhecido como β-ceto-N-methylbenzodioxolylbutanamine, é um entactogen, psicodélico, e estimulante droga psicoativa da fenetilamina classe química. Butylone foi sintetizado pela primeira vez por koeppe bosque, Ludwig, e Zeile em 1967. Ele permaneceu obscura produto da academia até 2005

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Butylone can be synthesized in a laboratory via the following route: 3,4-methylenedioxybutyrophenone dissolved in dichloromethane to bromine gives 3′,4′-methylenedioxy-2-bromobutyrophenone.

This product was then dissolved in dichloromethane and added to an aqueous solution of methylamine (40%). HCl was then added. The aqueous layer was removed and made alkaline by using sodium bicarbonate. For the extraction of the amine ether was used. To get butylone a drop of ether and HCl solution was added

Butylone acts in a similar way as MDMA and Methylone, it causes an increase in extracellular monoamine levels
Butylone was first synthesized by Koeppe, Ludwig and Zeile which is mentioned in their 1967 paper. It remained an obscure product of academia until 2005 when it was sold as a designer drug.[1] Butylone shares the same relationship to MBDB as methylone does to MDMA (“Ecstasy”). Formal research on this chemical was first conducted in 2009, when it was shown to be metabolised in a similar manner to related drugs like methylone
Butylone, also known as β-keto-N-methylbenzodioxolylbutanamine (βk-MBDB), is an entactogen, psychedelic, and stimulant psychoactive drug of the phenethylamine chemical class. It is the β-keto (substituted cathinone) analogue of MBDB and the substituted methylenedioxyphenethylamine analogue of buphedrone

There are three major metabolic pathways of bk-MBDB as shown in the figure. As result of demethylenation followed by O-methylation bk-MBDB metabolises into 4-OH-3-MeO and 3-OH-4-MeO metabolites in human urine. The second pathway is a β-ketone reduction into β-ketone reduced metabolites.

O terceiro caminho é a N-dealkylation em N-dealkyl metabólitos. As duas primeiras vias de ocorrer mais do que caminho de três. O mais comum metabólito é o 4-OH-3-MeO metabólito. Os metabólitos que contém uma hidroxila-grupo seria excretado como seus conjugados na urina