Dilaudid Hydromorphone 4mg

Dilaudid Hydromorphone 4mg

Dilaudid Hydromorphone 4mg a hydrogenated ketone of morphine, is an opioid agonist.

Dilaudid Hydromorphone 4mg is available as a sterile, aqueous solution is clear and colorless pre-filled syringes for slow intravenous, subcutaneous, or intramuscular administration. Each 1 mL pre-filled syringe contains 0.5 mg, 1 mg, 2 mg, or 4 mg of hydromorphone hydrochloride.

Dilaudid Hydromorphone 4mg is available as a sterile, aqueous solution in clear pre-filled syringes with a dark grey plunger rod, for slow intravenous, subcutaneous, or intramuscular administration. Each pre-filled syringe contains 10 mg/mL of hydromorphone hydrochloride.

The chemical name of DILAUDID is 4,5α-epoxy-3-hydroxy-17-methylmorphinan-6-one hydrochloride. The molecular weight is 321.80. Its molecular formula is C17H19NO3·HCl, and it has the following chemical structure:

Hydromorphone hydrochloride is a white or almost white crystalline powder that is freely soluble in water, very slightly soluble in ethanol (96%), and practically insoluble in methylene chloride.

The inactive ingredients in DILAUDID (hydromorphone hydrochloride) include 0.2% sodium citrate and 0.2% citric acid added as a buffer to maintain a pH between 3.5 and 5.5.

INDICATIONS

is indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

Dilaudid Hydromorphone 4mg is indicated for use in opioid-tolerant patients who require higher doses of opioids for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

Patients considered opioid tolerant are those who are taking for one week or longer,around-the-clock medicine consisting of at least 60 mg oral morphine per day, or at least 25 mcg transdermal fentanyl per hour, or at least 30 mg oral oxycodone per day, or at least 8 g oral hydromorphone per day, or at least 25 mg oral oxymorphone per day, or at least 60 mg oral hydrocodone per day, or an equianalgesic dose of another opioid for one week or longer. Patients must remain on around-the-clock opioids while administering DILAUDID-HP.

Limitations Of Use

Because of the risks of addiction, abuse, and misuse with opioids, even at recommended doses, reserve DILAUDID Dilaudid Hydromorphone 4mg for use in patients for whom alternative treatment options [e.g., non-opioid analgesics or opioid combination products

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