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Therapeutic Indications
For the short term treatment of severe, intractable insomnia in patients already
taking barbiturates. New patients should not be started on this preparation.
SECONAL SODIUM CAPSULES 100MG Attempts should be made to wean patients off this preparation by gradual
reduction of the dose over a period of days or weeks (see drug abuse and
SECONAL SODIUM CAPSULES 100MG
dependence). Abrupt discontinuation should be avoided as this may
precipitate withdrawal effects (see warnings).
SECONAL SODIUM CAPSULES 100MG 
Prosom - Clinical Pharmacology
Pharmacokinetics
Absorption
Prosom tablets have been found to be equivalent in absorption to an orally administered solution of estazolam. In healthy subjects who received up to three times the recommended dose of Prosom, peak estazolam plasma concentrations occurred within two hours after dosing (range 0.5 to 6.0 hours) and were proportional to the administered dose, suggesting linear pharmacokinetics over the dosage range tested. Prosom (Estazolam) 1mg
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