Prosom(艾司唑仑)1mg
Prosom(艾司唑仑)1mg a triazolobenzodiazepine derivative, is an oral hypnotic agent. Estazolam occurs as a fine, white, odorless powder that is soluble in alcohol and practically insoluble in water. The chemical name for estazolam is 8−chloro−6−phenyl−4H−s−triazolo[4,3-α] [1,4]benzodiazepine. The empirical formula is C16H11ClN4. The structural formula is represented as follows:
Prosom tablets are scored and contain either 1 mg or 2 mg of estazolam.
Inactive Ingredients
Colloidal silicon dioxide, lactose, povidone, stearic acid, and sodium starch glycolate.
Prosom(艾司唑仑)1mg
此外,2毫克片剂含有FD&C红色40号.
Prosom - Clinical Pharmacology
Pharmacokinetics
Absorption
Prosom tablets have been found to be equivalent in absorption to an orally administered solution of estazolam. In healthy subjects who received up to three times the recommended dose of Prosom, peak estazolam plasma concentrations occurred within two hours after dosing (range 0.5 to 6.0 hours) and were proportional to the administered dose, suggesting linear pharmacokinetics over the dosage range tested.
Prosom(艾司唑仑)1mg
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