Keytruda 50 mg Injektion
Keytruda 50 mg Injektioner et humaniseret monoklonalt antistof, der blokerer samspillet mellem PD-1 og dens ligander, PD-L1 og PD-L2. Pembrolizumab er en IgG4 immunglobulin kappa med en omtrentlig molekylære vægt af 149 kDa. Pembrolizumab er produceret i rekombinant Chinese hamster ovary (CHO) celler.
KEYTRUDA til injektion er en steril, konserveringsmiddel-fri, hvide til off-white frysetørrede pulver i enkelt dosis hætteglas. Hvert hætteglas er rekonstituerede og fortyndede til intravenøs infusion. Hver 2 mL rekonstitueret opløsning indeholder 50 mg af pembrolizumab og er formuleret i L-histidin (3.1 mg), polysorbat 80 (0,4 mg) og saccharose (140 mg). Kan indeholde saltsyre/natriumhydroxid til at justere pH-værdi på 5,5.
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Therapeutic Indications
For the short term treatment of severe, intractable insomnia in patients already
taking barbiturates. New patients should not be started on this preparation.
SECONAL SODIUM CAPSULES 100MG Attempts should be made to wean patients off this preparation by gradual
reduction of the dose over a period of days or weeks (see drug abuse and
SECONAL SODIUM CAPSULES 100MG
dependence). Abrupt discontinuation should be avoided as this may
precipitate withdrawal effects (see warnings).
SECONAL SODIUM CAPSULES 100MG 
Prosom - Clinical Pharmacology
Pharmacokinetics
Absorption
Prosom tablets have been found to be equivalent in absorption to an orally administered solution of estazolam. In healthy subjects who received up to three times the recommended dose of Prosom, peak estazolam plasma concentrations occurred within two hours after dosing (range 0.5 to 6.0 hours) and were proportional to the administered dose, suggesting linear pharmacokinetics over the dosage range tested. Prosom (Estazolam) 1mg
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